The biggest spread of the week is Falcons vs Rams, which sits at 11.5 in favor of LA. Odds as of September 11th at FanDuel Sportsbook. The table below lists the opening odds (point spread, moneyline, and game total) for all Week 2 games currently on the board. The Bills are favored by 9.5 points and the Eagles are 2.5-point picks. There will be two games on Monday Night Football with the Buffalo Bills hosting the Tennessee Titans and the Minnesota Vikings visiting the Philadelphia Eagles. Sunday Night Football will feature the Chicago Bears, who are 8.5-point underdogs, visiting the Green Bay Packers. The Chiefs have opened as 2.5-point favorites in the Week 2 NFL odds. Week 2 of the NFL season gets underway Thursday night when the Kansas City Chiefs host the Los Angeles Chargers. A look all the NFL Week 2 opening odds can be found below.The Lions are the smallest favorites by 1.5 points over the Commanders.The Rams are the biggest favorites in the NFL Week 2 opening odds by 11.5 points over the Falcons.Inglewood, California, USA Los Angeles Rams wide receiver Cooper Kupp (10) warms up before the game against the Buffalo Bills at SoFi Stadium.

Las vegas betting lines nfl week 9